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  Indian J Med Microbiol
 

Figure 5: Impact of KF in testicular damage after prolonged testicular cord torsion. Testicular histopathology. Representative microphotographs of sections of contralateral testis from rats (a) untreated or (b) treated with KF. Germ cell sloughing and seminiferous tubule atrophy in an untreated rat. Normal histology in a rat treated with KF. Scale bars = 100 μm. Quantitative assessment of tubular damage shows that (c) the mean tubular diameter and (d) Johnsen score are higher in KF versus vehicle group (P = 0.003 and P = 0.008, respectively). Horizontal lines represent the mean. Each symbol represents a single rat. (Mann–Whitney U test). KF: ketotifen fumarate.

Figure 5: Impact of KF in testicular damage after prolonged testicular cord torsion. Testicular histopathology. Representative microphotographs of sections of contralateral testis from rats (a) untreated or (b) treated with KF. Germ cell sloughing and seminiferous tubule atrophy in an untreated rat. Normal histology in a rat treated with KF. Scale bars = 100 μm. Quantitative assessment of tubular damage shows that (c) the mean tubular diameter and (d) Johnsen score are higher in KF versus vehicle group (<i>P</i> = 0.003 and <i>P</i> = 0.008, respectively). Horizontal lines represent the mean. Each symbol represents a single rat. (Mann–Whitney U test). KF: ketotifen fumarate.