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  Indian J Med Microbiol
 

Figure 1: Signaling pathway of the extrinsic factors, glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2). GDNF is the main extrinsic factor for maintaining undifferentiated spermatogonia. FGF2 signaling interacts with GDNF and is more likely to enhance proliferation rate.

Figure 1: Signaling pathway of the extrinsic factors, glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2). GDNF is the main extrinsic factor for maintaining undifferentiated spermatogonia. FGF2 signaling interacts with GDNF and is more likely to enhance proliferation rate.