Psychological burden prediction based on demographic variables among infertile men with sexual dysfunction
Hai-Ming Cao1, Zi Wan2, Yong Gao3, Jun-Long Zhang4, Yan Zhang5, Hai-Peng Xiao6, Xiang-An Tu7, Xiang-Zhou Sun8, Chun-Hua Deng9
1 Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Department of Urology, The Second Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China
Reproductive Medicine Center, The Key Laboratory for Reproductive Medicine of Guangdong Province, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Department of Cardiovascular, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Department of Andrology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Correspondence Address:
Chun-Hua Deng Department of Andrology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 China Yong Gao Reproductive Medicine Center, The Key Laboratory for Reproductive Medicine of Guangdong Province, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080 China
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/aja.aja_86_18
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There has been increasing interest in the psycho-socio-relational and sexual disorders of infertility, as the risk of psychological burden among infertile men with sexual dysfunctions is significant. The purpose of this study was to develop and to validate a predictive model to estimate individual psychological burden among infertile men with sexual dysfunction and study the association between them. Comprehensive data were collected for infertile men (n = 480) who sought treatment for infertility in a reproductive medicine center between June 2012 and December 2013. Using independent predictors of psychological burden from the least absolute shrinkage and selection operator, univariable and multivariable analyses were developed into two models. Predictive accuracy was compared between the models. We explored the association between sexual dysfunction and psychological burden. A total of 480 patients were analyzed using 10-fold cross-validation. Independent predictors of psychological burden were incorporated into a model to measure anxiety (corrected-area under curve (AUC): 77.3%) and a model to measure depression (corrected-AUC: 70.2%). Anxiety and depression were both associated with erectile dysfunction (P < 0.05), with anxiety demonstrating the strongest association. Only anxiety was associated with premature ejaculation (P < 0.05). Premature ejaculation was not found to be associated with depression (P > 0.05). Predictive models for psychological burden among infertile men with sexual dysfunction are presented, and we found that there is an association between psychological burden and sexual dysfunction. According to the models, proper counseling and treatment of sexual dysfunction in infertile men may reduce the psychological burden, help attain natural pregnancy, and improve the quality of life.
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