INVITED REVIEW |
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Year : 2015 | Volume
: 17
| Issue : 3 | Page : 421-426 |
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Germline-competent stem cell in avian species and its application
Jae Yong Han1, Hyung Chul Lee1, Tae Sub Park2
1 Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul-151 921, Korea 2 Graduate School of International Agricultural Technology and Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang-gun, Gangwon-do 232-916, Korea
Correspondence Address:
Jae Yong Han Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul-151 921 Korea
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1008-682X.148073
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Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds. |
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